- Abstract:
-
Several nuclear localised intergenic long noncoding RNAs (lncRNAs) have been ascribed regulatory roles in transcriptional control and their number is growing rapidly. Initially, these transcripts were shown to function locally, near their sites of synthesis, by regulating the expression of neighbouring genes. More recently, lncRNAs have been demonstrated to interact with chromatin at several thousand different locations across multiple chromosomes and to modulate large-scale gene expression p...
Expand abstract - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Publisher's version
- Files:
-
-
(pdf, 517.1KB)
-
- Publisher copy:
- 10.1016/j.tig.2014.06.001
-
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- Publisher:
- Cell Press Publisher's website
- Journal:
- Trends in Genetics Journal website
- Volume:
- 30
- Issue:
- 8
- Pages:
- 348–355
- Publication date:
- 2014-01-01
- DOI:
- ISSN:
-
0168-9525
- URN:
-
uuid:85c40e0c-bc75-45fd-afad-19b9978757f5
- Source identifiers:
-
474859
- Local pid:
- pubs:474859
- Language:
- English
- Keywords:
- Copyright holder:
- Vance and Ponting
- Copyright date:
- 2014
- Notes:
-
Copyright © 2014 The Authors. Published by Elsevier Ltd. This is an open access article under
the CC BY license (http://creativecommons.org/licenses/by/3.0/). Open Access funded by European Research Council.
Journal article
Transcriptional regulatory functions of nuclear long noncoding RNAs
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