Journal article icon

Journal article

Transcriptional regulatory functions of nuclear long noncoding RNAs

Abstract:

Several nuclear localised intergenic long noncoding RNAs (lncRNAs) have been ascribed regulatory roles in transcriptional control and their number is growing rapidly. Initially, these transcripts were shown to function locally, near their sites of synthesis, by regulating the expression of neighbouring genes. More recently, lncRNAs have been demonstrated to interact with chromatin at several thousand different locations across multiple chromosomes and to modulate large-scale gene expression p...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

Actions


Access Document


Files:
Publisher copy:
10.1016/j.tig.2014.06.001

Authors


More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Physiology Anatomy and Genetics
Role:
Author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Physiology Anatomy and Genetics
Role:
Author
European Research Council More from this funder
Medical Research Council More from this funder
Publisher:
Cell Press Publisher's website
Journal:
Trends in Genetics Journal website
Volume:
30
Issue:
8
Pages:
348–355
Publication date:
2014-01-01
DOI:
ISSN:
0168-9525
URN:
uuid:85c40e0c-bc75-45fd-afad-19b9978757f5
Source identifiers:
474859
Local pid:
pubs:474859

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP