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Journal article

Nimesulide improves the disease modifying anti-rheumatic profile of methotrexate in mice with collagen-induced arthritis.

Abstract:

Methotrexate is a disease modifying anti-rheumatic drug that is widely used for the treatment of rheumatoid arthritis. Nimesulide is a non-steroidal anti-inflammatory drug which is frequently used as adjuvant therapy for symptomatic alleviation of rheumatoid arthritis. In this study, we have evaluated the potential influence of nimesulide on the disease modifying anti-rheumatic properties of methotrexate using the collagen-induced arthritis model. Mice were immunized with collagen type II for...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, NDORMS
Role:
Author
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Journal:
European journal of pharmacology
Volume:
644
Issue:
1-3
Pages:
245-250
Publication date:
2010-10-05
DOI:
EISSN:
1879-0712
ISSN:
0014-2999
URN:
uuid:85c24e53-6af6-4afb-8e1b-4520257b28c5
Source identifiers:
226961
Local pid:
pubs:226961

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