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Journal article

Electron cryotomography of Tula hantavirus suggests a unique assembly paradigm for enveloped viruses.

Abstract:

Hantaviruses (family Bunyaviridae) are rodent-borne emerging viruses that cause a serious, worldwide threat to human health. Hantavirus diseases include hemorrhagic fever with renal syndrome and hantavirus cardiopulmonary syndrome. Virions are enveloped and contain a tripartite single-stranded negative-sense RNA genome. Two types of glycoproteins, G(N) and G(C), are embedded in the viral membrane and form protrusions, or "spikes." The membrane encloses a ribonucleoprotein core, which consists...

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Publication status:
Published

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Publisher copy:
10.1128/jvi.00057-10

Authors


Huiskonen, JT More by this author
Hepojoki, J More by this author
Laurinmäki, P More by this author
Lankinen, H More by this author
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Journal:
Journal of virology
Volume:
84
Issue:
10
Pages:
4889-4897
Publication date:
2010-05-05
DOI:
EISSN:
1098-5514
ISSN:
0022-538X
URN:
uuid:858d10ba-dea4-4a26-8b9e-832add21a551
Source identifiers:
66882
Local pid:
pubs:66882

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