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Commentary. A picture of Mitf in melanoma immortality.

Abstract:
The Mitf gene has a key role in melanocytes and melanoma by regulating cell cycle progression, survival and differentiation. Two papers in this issue of Oncogene (Cheli et al., 2011; Strub et al., 2011) reveal that low-Mitf cells can initiate tumors with high efficiency, and that Mitf blocks senescence by regulating genes implicated in S-phase progression and mitosis.
Publication status:
Published

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Publisher copy:
10.1038/onc.2010.641

Authors


Goding, CR More by this author
Journal:
Oncogene
Volume:
30
Issue:
20
Pages:
2304-2306
Publication date:
2011-05-05
DOI:
EISSN:
1476-5594
ISSN:
0950-9232
URN:
uuid:85668627-3d8a-444c-8f43-a982891b6fb4
Source identifiers:
149926
Local pid:
pubs:149926

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