- Abstract:
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Autoantibodies directed against the P450 side chain cleavage enzyme (P450scc) have been recently described in dogs affected with hypoadrenocorticism, consistent with an immune-mediated pathogenesis of this endocrinopathy. In human autoimmune Addison’s disease, autoantibodies may have a predictive value, being detectable before clinical signs developing, and have been shown to persist for a period of time after diagnosis. Furthermore, an autoantibody positive status post-diagnosis has been ass...
Expand abstract - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Accepted Manuscript
- Files:
-
-
(pdf, 206.7KB)
-
- Publisher copy:
- 10.1016/j.vetimm.2018.05.013
-
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- Publisher:
- Elsevier Publisher's website
- Journal:
- Veterinary Immunology and Immunopathology Journal website
- Volume:
- 202
- Pages:
- 41-45
- Publication date:
- 2018-05-26
- Acceptance date:
- 2018-05-25
- DOI:
- ISSN:
-
0165-2427
- Pubs id:
-
pubs:858733
- URN:
-
uri:8564dfbd-6120-4bee-ad4a-75d00d1ceea2
- UUID:
-
uuid:8564dfbd-6120-4bee-ad4a-75d00d1ceea2
- Local pid:
- pubs:858733
- Copyright holder:
- Elsevier B.V.
- Copyright date:
- 2018
- Notes:
-
Copyright © 2018 Elsevier B.V. This is the accepted manuscript version of the article. The final version is available online from Elsevier at: https://doi.org/10.1016/j.vetimm.2018.05.013
Journal article
A longitudinal study of autoantibodies against cytochrome P450 side-chain cleavage enzyme in dogs (Canis lupus familiaris) affected with hypoadrenocorticism (Addison’s disease)
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Dechra Ltd
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