Journal article
A longitudinal study of autoantibodies against cytochrome P450 side-chain cleavage enzyme in dogs (Canis lupus familiaris) affected with hypoadrenocorticism (Addison’s disease)
- Abstract:
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Autoantibodies directed against the P450 side chain cleavage enzyme (P450scc) have been recently described in dogs affected with hypoadrenocorticism, consistent with an immune-mediated pathogenesis of this endocrinopathy. In human autoimmune Addison’s disease, autoantibodies may have a predictive value, being detectable before clinical signs developing, and have been shown to persist for a period of time after diagnosis. Furthermore, an autoantibody positive status post-diagnosis has been ass...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Files:
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(Accepted manuscript, pdf, 206.7KB)
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- Publisher copy:
- 10.1016/j.vetimm.2018.05.013
Authors
Funding
Dechra Ltd
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Bibliographic Details
- Publisher:
- Elsevier Publisher's website
- Journal:
- Veterinary Immunology and Immunopathology Journal website
- Volume:
- 202
- Pages:
- 41-45
- Publication date:
- 2018-05-26
- Acceptance date:
- 2018-05-25
- DOI:
- ISSN:
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0165-2427
- Source identifiers:
-
858733
Item Description
- Keywords:
- Pubs id:
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pubs:858733
- UUID:
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uuid:8564dfbd-6120-4bee-ad4a-75d00d1ceea2
- Local pid:
- pubs:858733
- Deposit date:
- 2018-06-21
Terms of use
- Copyright holder:
- Elsevier BV
- Copyright date:
- 2018
- Notes:
- Copyright © 2018 Elsevier B.V. This is the accepted manuscript version of the article. The final version is available online from Elsevier at: https://doi.org/10.1016/j.vetimm.2018.05.013
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