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Animal models of intestinal inflammation: clues to the pathogenesis of inflammatory bowel disease.

Abstract:

In the last decade a number of models of chronic intestinal inflammation have been described that resemble aspects of the pathology found in patients with inflammatory bowel disease. Several themes have emerged from these studies that are of relevance to the pathogenesis of inflammatory bowel disease. Firstly, intestinal inflammation is a consequence of an aberrant chronic immune response triggered by enteric bacteria. Both innate and adaptive immune mechanisms can cause colitis and in many m...

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Experimental Medicine Division,
Role:
Author
Journal:
Novartis Foundation symposium
Volume:
263
Pages:
164-218
Publication date:
2004-01-01
EISSN:
1935-4657
ISSN:
1528-2511
URN:
uuid:85401cfd-8951-4a3d-b480-6de6145b777d
Source identifiers:
618
Local pid:
pubs:618

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