Structural and functional bases of visuospatial associative memory in older adults.

Journal article

Impaired visuospatial associative memory may be one of the earliest changes predicting cognitive impairment and Alzheimer's disease. We explored the relationship between performance on a visuospatial associative memory task (the Placing Test) and brain structure and function in cognitively healthy older adults. First, we performed a voxel-based morphometry correlational analysis on structural magnetic resonance imaging (MRI) data from 144 healthy older adults with their scores on the Placing ...

Expand abstract

Authors: Zamboni, G; de Jager, C; Drazich, E; Douaud, G; Jenkinson, M

• Publication status: Published
• Journal: Neurobiology of aging
• Volume: 34
• Issue: 3
• Pages: 961-972
• Publication date: 2013-03-01
• DOI: 10.1016/j.neurobiolaging.2012.07.011
• EISSN: 1558-1497
• ISSN: 0197-4580
• Language: English
• Keywords: Humans; Neuropsychological Tests; Middle Aged; Association Learning; Female; Functional Neuroimaging; Magnetic Resonance Imaging; Male; Cohort Studies; Atrophy; Aged, 80 and over; Memory Disorders; Temporal Lobe; Aging; Prospective Studies; Aged; Memory; Hippocampus