Journal article
Hypoxia and hypoxia mimetics differentially modulate histone post-translational modifications
- Abstract:
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Post-translational modifications (PTMs) to the tails of the core histone proteins are critically involved in epigenetic regulation. Hypoxia affects histone modifications by altering the activities of histone-modifying enzymes and the levels of hypoxia-inducible factor (HIF) isoforms. Synthetic hypoxia mimetics promote a similar response, but how accurately the hypoxia mimetics replicate the effects of limited oxygen availability on the levels of histone PTMs is uncertain. Here we report studi...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Files:
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(Supplementary materials, 6.3MB)
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(Version of record, 8.9MB)
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- Publisher copy:
- 10.1080/15592294.2020.1786305
Authors
Funding
Bibliographic Details
- Publisher:
- Taylor & Francis Publisher's website
- Journal:
- Epigenetics Journal website
- Volume:
- 16
- Issue:
- 1
- Pages:
- 14-27
- Publication date:
- 2020-07-01
- Acceptance date:
- 2020-05-22
- DOI:
- EISSN:
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1559-2308
- ISSN:
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1559-2294
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
1107800
- Local pid:
- pubs:1107800
- Deposit date:
- 2020-06-01
Terms of use
- Copyright holder:
- Hsu et al.
- Copyright date:
- 2020
- Rights statement:
- © 2020 The Authors. Published by Informa UK Limited, trading as Taylor & Francis Group. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
- Licence:
- CC Attribution (CC BY)
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