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Hox gene evolution in nematodes: novelty conserved.

Abstract:

The conserved homeobox (Hox) gene cluster is neither conserved nor clustered in the nematode Caenorhabditis elegans. Instead, C. elegans has a reduced and dispersed gene complement that is the result the loss of Hox genes in stages throughout its evolutionary history. The roles of Hox genes in patterning the nematode body axis are also divergent, although there are tantalising remnants of ancient regulatory systems. Hox patterning also differs greatly between C. elegans and a second 'model' n...

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Publisher copy:
10.1016/j.gde.2003.10.009

Authors


Aboobaker, A More by this author
Blaxter, M More by this author
Journal:
Current opinion in genetics and development
Volume:
13
Issue:
6
Pages:
593-598
Publication date:
2003-12-05
DOI:
EISSN:
1879-0380
ISSN:
0959-437X
URN:
uuid:8512e74f-e5e0-4553-bc1e-bcbd5eca40c9
Source identifiers:
383071
Local pid:
pubs:383071

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