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In vitro studies of the efficiency of two-photon activation of photodynamic therapy agents

Abstract:

Age related macular degeneration (AMD) is a major cause of severe vision loss in the older population, due to ingrowth of new leaky blood vessels (neovasculature) from the choriocapillaris, which results in destruction of photoreceptors in the fovea and loss of central vision. "Standard" one-photon (1-γ) photodynamic therapy (PDT) using Visudyne® is an approved method of AMD treatment but has the potential to damage healthy tissues lying above and below the neovasculature due to photosensitiz...

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Publisher copy:
10.1117/12.706554

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Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Sub department:
Organic Chemistry
Role:
Author
Journal:
Proceedings of SPIE - The International Society for Optical Engineering
Volume:
6343 I
Publication date:
2006-01-01
DOI:
ISSN:
0277-786X
Source identifiers:
331925
Language:
English
Keywords:
Pubs id:
pubs:331925
UUID:
uuid:84f75565-d651-4b23-b625-97c11501b6bf
Local pid:
pubs:331925
Deposit date:
2012-12-19

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