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In vitro studies of the efficiency of two-photon activation of photodynamic therapy agents

Abstract:

Age related macular degeneration (AMD) is a major cause of severe vision loss in the older population, due to ingrowth of new leaky blood vessels (neovasculature) from the choriocapillaris, which results in destruction of photoreceptors in the fovea and loss of central vision. "Standard" one-photon (1-γ) photodynamic therapy (PDT) using Visudyne® is an approved method of AMD treatment but has the potential to damage healthy tissues lying above and below the neovasculature due to photosensitiz...

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Publisher copy:
10.1117/12.706554

Authors


Khurana, M More by this author
Karotki, A More by this author
Collins, H More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MPLS, Chemistry, Organic Chemistry
Wilson, BC More by this author
Journal:
Proceedings of SPIE - The International Society for Optical Engineering
Volume:
6343 I
Publication date:
2006
DOI:
ISSN:
0277-786X
URN:
uuid:84f75565-d651-4b23-b625-97c11501b6bf
Source identifiers:
331925
Local pid:
pubs:331925

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