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Journal article

Defining the molecular profile of planarian pluripotent stem cells using a combinatorial RNAseq, RNA interference and irradiation approach.

Abstract:

BACKGROUND: Planarian stem cells, or neoblasts, drive the almost unlimited regeneration capacities of freshwater planarians. Neoblasts are traditionally described by their morphological features and by the fact that they are the only proliferative cell type in asexual planarians. Therefore, they can be specifically eliminated by irradiation. Irradiation, however, is likely to induce transcriptome-wide changes in gene expression that are not associated with neoblast ablation. This has affected...

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Publication status:
Published
Peer review status:
Peer reviewed

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Files:
Publisher copy:
10.1186/gb-2012-13-3-r19

Authors


Publisher:
BioMed Central Publisher's website
Journal:
Genome biology Journal website
Volume:
13
Issue:
3
Pages:
R19
Publication date:
2012-01-01
DOI:
EISSN:
1465-6914
ISSN:
1465-6906
Language:
English
Keywords:
UUID:
uuid:84e6e5f8-ded4-48a8-85a0-43bf4d3271e2
Local pid:
pubs:383069
Source identifiers:
383069
Deposit date:
2013-11-16

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