Journal article icon

Journal article

Molecular mechanisms of cytoadherence in malaria

Abstract:

Microbial pathosens subvert host adhesion molecules to dissemi-nate or to enter host cells to promote their own survival. One such subversion is the cytoadherence of Plasmodium falciparum-infected erythrocytes (IRBC) to vascular endothelium, which protects the parasite from being removed by the spleen. The process results in microcirculatory obstruction and subsequent hypoxia, metabolic disturbances, and multiorgan failure, which are detrimental to the host. Understanding the molecular events...

Expand abstract

Actions


Authors


More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Thailand/Laos MOP
Role:
Author
Journal:
American Journal of Physiology
Volume:
276
Issue:
6 PART 1
Publication date:
1999-01-01
ISSN:
0002-9513
URN:
uuid:84d42330-1bc1-410b-bb69-4c142493f214
Source identifiers:
80066
Local pid:
pubs:80066

Terms of use


Metrics


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP