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Journal article

Microsatellite analysis of early stage (Ia-IIb) uterine cervical squamous carcinoma.

Abstract:

Cervical cancer is the most common gynecologic malignancy of the developing world. The oncogenic role of human papilloma virus (HPV) is well known. Attention is now focusing on the complicit genetic changes, which allow progression of these tumors. Regarding these changes, deletion of tumor suppressor genes (loss of heterozygosity [LOH]) is the preferred pathway of progression with only a subset manifesting microsatellite instability (MSI). Implicated loci include 3p14.1-22. Several studies s...

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Publication status:
Published

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Publisher copy:
10.1177/106689690301100402

Authors


Moodley, M More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, RDM, Clinical Lab Sciences, Biomedical Research Centre
Journal:
International journal of surgical pathology
Volume:
11
Issue:
4
Pages:
253-260
Publication date:
2003-10-05
DOI:
EISSN:
1940-2465
ISSN:
1066-8969
URN:
uuid:84ade703-d509-4931-a32e-9f5c5a71062a
Source identifiers:
122032
Local pid:
pubs:122032

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