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A new tracer method for the calculation of rates of bone formation and breakdown in osteoporosis and other generalised skeletal disorders

Abstract:

1. Evidence has accumulated that the rate of acceretion (A) of calcium to bone is the sum of two fluxes; apposition involving the laying down of new bone and augmentation which is the result of slow exchange of non-surface bone calcium with plasma calcium pools as the result of solid state diffusion. 2. A method has been devised for separating A into its two components. It requires the use of45Ca or, for clinical studies,85Sr as a calcium tracer. Studies which are initiated with a combined ac...

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Publisher copy:
10.1007/BF02010358

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Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Role:
Author
Publisher:
Springer-Verlag
Journal:
Calcified Tissue Research
Volume:
22
Issue:
1
Pages:
191-206
Publication date:
1977-12-01
DOI:
EISSN:
1432-0827
ISSN:
0008-0594
Source identifiers:
473701
Language:
English
Keywords:
Pubs id:
pubs:473701
UUID:
uuid:84ad4f45-ef91-4cba-a4b8-256889054255
Local pid:
pubs:473701
Deposit date:
2014-09-22

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