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Iminosugars as therapeutic agents: recent advances and promising trends.

Abstract:

For the purpose of this article, iminosugars are polyhydroxylated secondary and tertiary amines in which the molecules resemble monosaccharide sugars in which the ring oxygen is replaced by the nitrogen. The bicyclic structures may biologically resemble disaccharides. Very few iminosugars have been available up to now for evaluation of their pharmaceutical applications. The early compounds were discovered and selected for study due to glycosidase inhibition, which is now known to not be neces...

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Publication status:
Published

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Publisher copy:
10.4155/fmc.11.117

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Institution:
University of Oxford
Department:
Oxford, MPLS, Chemistry, Organic Chemistry
Journal:
Future medicinal chemistry
Volume:
3
Issue:
12
Pages:
1513-1521
Publication date:
2011-09-05
DOI:
EISSN:
1756-8927
ISSN:
1756-8919
URN:
uuid:848a4cc5-90c2-4967-acff-66f8dc529c9c
Source identifiers:
192874
Local pid:
pubs:192874

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