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Inhibition of vasomotion in hippocampal cerebral arterioles during increases in neuronal activity.

Abstract:

The activity of small arterioles, internal diameter 9.9 +/- 0.8 microm (SEM), was investigated in the CA1 region of hippocampal slices maintained in vitro at 34 degrees C. Under resting conditions, the vessels were quiescent. However, in the presence of the thromboxane A2 agonist U46619 (75-100 nM), rhythmic contractile activity (vasomotion, 1.1-9.9 min(-1), mean 4.1 +/- 0.7 min(-1) SEM) developed in the smooth muscle cells of the vessel walls. Electrical stimulation of the Schaffer collatera...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neuroscience
Role:
Author
Journal:
Autonomic neuroscience : basic and clinical
Volume:
95
Issue:
1-2
Pages:
137-140
Publication date:
2002-01-05
DOI:
EISSN:
1872-7484
ISSN:
1566-0702
URN:
uuid:847405ba-956e-43b3-884c-2cfa6782b0d1
Source identifiers:
102625
Local pid:
pubs:102625

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