- Abstract:
-
The macrophage-specific antigen F4/80 has been localized in mouse lymphoid and hematopoietic tissue and skin using immunoperoxidase staining. The antigen permits identification of early mononuclear phagocyte precursors in the bone marrow, and is present also on larger cells forming the center of hematopoietic islands and lining vascular sinuses. In thymus F4/80+ cells are numerous in both cortex and medulla and are particularly concentrated around the corticomedullary region. In spleen, lymph...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1084/jem.158.5.1522
-
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- Journal:
- The Journal of experimental medicine
- Volume:
- 158
- Issue:
- 5
- Pages:
- 1522-1536
- Publication date:
- 1983-11-05
- DOI:
- EISSN:
-
1540-9538
- ISSN:
-
0022-1007
- URN:
-
uuid:8463b884-1290-48b3-bd5f-66c07840f82b
- Source identifiers:
-
31234
- Local pid:
- pubs:31234
- Copyright date:
- 1983
Journal article
The mononuclear phagocyte system of the mouse defined by immunohistochemical localization of antigen F4/80. Relationship between macrophages, Langerhans cells, reticular cells, and dendritic cells in lymphoid and hematopoietic organs.
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