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Variation in the shape of pulsed arterial spin labeling kinetic curves across the healthy human brain and its implications for CBF quantification.

Abstract:

Arterial spin labeling (ASL) uses proximally inverted blood water spins as an endogenous contrast agent to measure blood perfusion in tissue. In this work pulsed ASL was used to measure the kinetic curves of cerebral blood flow (CBF) across eight anatomically based regions of interest (ROIs) in five normal healthy subjects. CBF estimates based on these data were compared when obtained using a single inversion time versus fitting a kinetic model to all 10 measured inversion times. CBF estimate...

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Publication status:
Published

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Publisher copy:
10.1002/mrm.21886

Authors


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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neuroscience
Role:
Author
Journal:
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine
Volume:
61
Issue:
3
Pages:
686-695
Publication date:
2009-03-05
DOI:
EISSN:
1522-2594
ISSN:
0740-3194
URN:
uuid:845f9375-09a5-4565-a174-56a9ee5944ab
Source identifiers:
241428
Local pid:
pubs:241428

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