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Journal article

Specificity of T cells in synovial fluid: high frequencies of CD8(+) T cells that are specific for certain viral epitopes.

Abstract:

INTRODUCTION: Epstein-Barr virus (EBV) is transmitted orally, replicates in the oropharynx and establishes life-long latency in human B lymphocytes. T-cell responses to latent and lytic/replicative cycle proteins are readily detectable in peripheral blood from healthy EBV-seropositive individuals. EBV has also been detected within synovial tissue, and T-cell responses to EBV lytic proteins have been reported in synovial fluid from a patient with rheumatoid arthritis (RA). This raises the ques...

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Publication status:
Published

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Publisher copy:
10.1186/ar80

Authors


Rostron, T More by this author
Roskell, H More by this author
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Journal:
Arthritis research
Volume:
2
Issue:
2
Pages:
154-164
Publication date:
2000
DOI:
EISSN:
1465-9913
ISSN:
1465-9905
URN:
uuid:845c3794-9b72-4001-8da6-6eedf51822ee
Source identifiers:
31770
Local pid:
pubs:31770

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