- Abstract:
-
Protein‐protein interactions (PPIs) are principle biological processes that control normal cell growth, differentiation, and homeostasis but are also crucial in diseases such as malignancy, neuropathy, and infection. Despite the importance of PPIs in biology, this target class has been very challenging to convert to therapeutics. In the last decade, much progress has been made in the inhibition of PPIs involved in diseases, but many remain difficult such as RAS‐effector interactions in cancer...
Expand abstract - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Files:
-
- Publisher copy:
- 10.1002/cpcb.83
-
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- Publisher:
- Wiley Publisher's website
- Journal:
- Current Protocols in Cell Biology Journal website
- Volume:
- 83
- Issue:
- 1
- Article number:
- e83
- Publication date:
- 2019-02-15
- Acceptance date:
- 2019-01-27
- DOI:
- EISSN:
-
1934-2616
- ISSN:
-
1934-2500
- Pmid:
-
30768855
- Pubs id:
-
pubs:974955
- UUID:
-
uuid:845a6c07-932f-4bc2-a63f-62e68c5980c2
- Source identifiers:
-
974955
- Local pid:
- pubs:974955
- Language:
- English
- Keywords:
- Copyright holder:
- John Wiley & Sons, Inc.
- Rights statement:
- © 2019 John Wiley & Sons, Inc.
- Notes:
- This is the accepted manuscript version of the article. The final version is available online from Wiley at: https://doi.org/10.1002/cpcb.83
Journal article
Bioluminescence Resonance Energy Transfer 2 (BRET2)‐based RAS biosensors to characterize RAS inhibitors
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