Journal article icon

Journal article

Paradoxical effects of short-term antidepressant treatment in fMRI emotional processing models in volunteers with high neuroticism.

Abstract:

BACKGROUND: Short-term antidepressant administration has been reported to decrease amygdala response to threat in healthy volunteers and depressed patients. Neuroticism (N) is a risk factor for depression but has also been associated with slow or incomplete remission with antidepressant drug treatment. Our aim was to investigate early selective serotonin reuptake inhibitor (SSRI) administration neural effects on implicit processing of fearful facial expressions in volunteers with high levels ...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1017/s0033291713000731

Authors


Di Simplicio, M More by this author
Norbury, R More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Psychiatry
Harmer, CJ More by this author
Journal:
Psychological medicine
Volume:
44
Issue:
2
Pages:
241-252
Publication date:
2014-01-05
DOI:
EISSN:
1469-8978
ISSN:
0033-2917
URN:
uuid:8430b15d-4db9-4071-aa93-748e19768259
Source identifiers:
395965
Local pid:
pubs:395965

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP