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Characterization of the CD200 receptor family in mice and humans and their interactions with CD200.

Abstract:

CD200 (OX2) is a broadly distributed cell surface glycoprotein that interacts with a structurally related receptor (CD200R) expressed on rodent myeloid cells and is involved in regulation of macrophage function. We report the first characterization of human CD200R (hCD200R) and define its binding characteristics to hCD200. We also report the identification of a closely related gene to hCD200R, designated hCD200RLa, and four mouse CD200R-related genes (termed mCD200RLa-d). CD200, CD200R, and C...

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Publication status:
Published

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Publisher copy:
10.4049/jimmunol.171.6.3034

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Journal:
Journal of immunology (Baltimore, Md. : 1950)
Volume:
171
Issue:
6
Pages:
3034-3046
Publication date:
2003-09-05
DOI:
EISSN:
1550-6606
ISSN:
0022-1767
URN:
uuid:840de1a1-8b53-4e39-9c48-f21cf993df80
Source identifiers:
14157
Local pid:
pubs:14157

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