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Journal article

Myasthenia gravis.

Abstract:

Myasthenia gravis is an autoimmune disorder mainly caused by antibodies to the muscle acetylcholine receptors (AChRs) at the neuromuscular junction. Loss of these receptors leads to a defect in neuromuscular transmission with muscle weakness and fatigue. AChR antibody tests are widely available and overall incidence and prevalence of the disorder seem to be rising, especially in elderly people. The disease is heterogeneous with respect to age at onset, thymic changes and distribution of muscl...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neuroscience
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neuroscience
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neuroscience
Journal:
Lancet
Volume:
357
Issue:
9274
Pages:
2122-2128
Publication date:
2001-06-05
DOI:
EISSN:
1474-547X
ISSN:
0140-6736
URN:
uuid:84061442-2b74-487c-a8b2-b77a04efc435
Source identifiers:
241280
Local pid:
pubs:241280
Language:
English
Keywords:

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