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Impact of host responses on control of hepatitis C virus infection in Chinese blood donors

Abstract:

A study was undertaken to explore the molecular mechanisms underlying control of HCV infection in blood donors in China. Factors including clinical information, anti-HCV reactivity (S/CO), IFN-α and IFN-γ, viral loads and genotypes were correlated with 160 index plasma samples at three statuses of 45 recovered, 76 chronic or 39 false positive anti-HCV reactive blood donors. The spontaneous recovery rate was 37.2%. Viral loads of 76 HCV plasmas ranged between 59.8IU/ml and 2.43×10 6IU/ml (medi...

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Publisher copy:
10.1016/j.bbrc.2011.10.102

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Journal:
Biochemical and Biophysical Research Communications
Volume:
415
Issue:
3
Pages:
503-508
Publication date:
2011-11-25
DOI:
EISSN:
1090-2104
ISSN:
0006-291X
URN:
uuid:83f79c30-2567-4d4f-beb8-a599e9333608
Source identifiers:
221540
Local pid:
pubs:221540
Language:
English
Keywords:

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