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Phenotyping the preterm brain: characterizing individual deviations from normative volumetric development in two large infant cohorts

Abstract:

The diverse cerebral consequences of preterm birth create significant challenges for understanding pathogenesis or predicting later outcome. Instead of focusing on describing effects common to the group, comparing individual infants against robust normative data offers a powerful alternative to study brain maturation. Here we used Gaussian process regression to create normative curves characterizing brain volumetric development in 274 term-born infants, modeling for age at scan and sex. We th...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1093/cercor/bhab039

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Role:
Author
ORCID:
0000-0002-6903-7990
Publisher:
Oxford University Press
Journal:
Cerebral Cortex More from this journal
Volume:
31
Issue:
8
Pages:
3665–3677
Publication date:
2021-04-05
Acceptance date:
2021-02-05
DOI:
EISSN:
1460-2199
ISSN:
1047-3211
Pmid:
33822913
Language:
English
Keywords:
Pubs id:
1171269
Local pid:
pubs:1171269
Deposit date:
2021-04-27

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