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Phospholipase Czeta, the trigger of egg activation in mammals, is present in a non-mammalian species.

Abstract:

The activation of the egg to begin development into an embryo is triggered by a sperm-induced increase in intracellular egg Ca2+. There has been much controversy about how the sperm induces this fundamental developmental event, but recent studies suggest that, in mammals, egg activation is triggered by a testis-specific phospholipase C: PLCzeta. Since the discovery of PLCzeta, it has been unclear whether its role in triggering egg activation is common to all vertebrates, or is confined to mam...

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Publication status:
Published

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Publisher copy:
10.1530/rep.1.00707

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Journal:
Reproduction (Cambridge, England)
Volume:
130
Issue:
2
Pages:
157-163
Publication date:
2005-08-05
DOI:
EISSN:
1741-7899
ISSN:
1470-1626
URN:
uuid:83dc033a-6035-4558-bfbd-1acfac582e30
Source identifiers:
185143
Local pid:
pubs:185143

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