Journal article
The relation between adult weight gain, adipocyte volume and the metabolic profile at middle age
- Abstract:
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Purpose Weight gain during adulthood increases cardiometabolic disease risk, possibly through adipocyte hypertrophy. We aimed to study the specific metabolomic profile of adult weight gain, and to examine its association with adipocyte volume. Methods Nuclear magnetic resonance-based metabolomics were measured in the Netherlands Epidemiology of Obesity (NEO) study (n=6 347, discovery) and Oxford Biobank (n=6 317, replication). Adult weight gain was calculated as the absolute difference betwe...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Preview, Version of record, 3.6MB, Terms of use)
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- Publisher copy:
- 10.1210/clinem/dgab477
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Funding
Bibliographic Details
- Publisher:
- Oxford University Press
- Journal:
- Journal of Clinical Endocrinology and Metabolism More from this journal
- Volume:
- 106
- Issue:
- 11
- Pages:
- e4438-e4447
- Publication date:
- 2021-06-28
- Acceptance date:
- 2021-05-03
- DOI:
- EISSN:
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1945-7197
- ISSN:
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0021-972X
Item Description
- Language:
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English
- Keywords:
- Pubs id:
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1184115
- Local pid:
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pubs:1184115
- Deposit date:
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2021-06-29
Terms of use
- Copyright holder:
- Verkouter et al.
- Copyright date:
- 2021
- Rights statement:
- © The Author(s) 2021. Published by Oxford University Press on behalf of the Endocrine Society. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited.
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