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Comparison of MAS-PCR and GenoType MTBDR assay for the detection of rifampicin-resistant Mycobacterium tuberculosis.

Abstract:

SETTING: Pham Ngoc Thach Hospital for Tuberculosis and Lung Diseases, the tertiary referral hospital for tuberculosis (TB) in Southern Vietnam. OBJECTIVE: To develop and evaluate a simple, rapid and accurate multiplex allele specific polymerase chain reaction (MAS-PCR) test to detect rifampicin (RMP) resistance point mutations at codons 516, 526 or 531 in the rpoB gene of Mycobacterium tuberculosis. DESIGN: The novel MAS-PCR was compared with the commercial M. tuberculosis Drug Resistance (MT...

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Publication status:
Published

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Journal:
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease
Volume:
12
Issue:
11
Pages:
1306-1312
Publication date:
2008-11-05
EISSN:
1815-7920
ISSN:
1027-3719
URN:
uuid:83d0b7d4-f397-4a60-93a9-4bf37f3a96be
Source identifiers:
34426
Local pid:
pubs:34426

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