Journal article
Hypoxia. HIF-mediated articular chondrocyte function: prospects for cartilage repair.
- Abstract:
-
In a chronically hypoxic tissue such as cartilage, adaptations to hypoxia do not merely include cell survival responses, but also promotion of its specific function. This review will focus on describing such hypoxia-mediated chondrocyte function, in particular in the permanent articular cartilage. The molecular details of how chondrocytes sense and respond to hypoxia and how this promotes matrix synthesis have recently been examined, and specific manipulation of hypoxia-induced pathways is no...
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- Publication status:
- Published
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- Publisher copy:
- 10.1186/ar2574
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Bibliographic Details
- Journal:
- Arthritis research and therapy
- Volume:
- 11
- Issue:
- 1
- Pages:
- 213
- Publication date:
- 2009-01-01
- DOI:
- EISSN:
-
1478-6362
- ISSN:
-
1478-6354
- Source identifiers:
-
226577
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:226577
- UUID:
-
uuid:83c48a8a-e7e0-4b75-a89b-12b06a5f29ef
- Local pid:
- pubs:226577
- Deposit date:
- 2013-11-16
Terms of use
- Copyright date:
- 2009
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