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GABAB(1) receptor subunit isoforms differentially regulate stress resilience.

Abstract:

Stressful life events increase the susceptibility to developing psychiatric disorders such as depression; however, many individuals are resilient to such negative effects of stress. Determining the neurobiology underlying this resilience is instrumental to the development of novel and more effective treatments for stress-related psychiatric disorders. GABAB receptors are emerging therapeutic targets for the treatment of stress-related disorders such as depression. These receptors are predomin...

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Publisher copy:
10.1073/pnas.1404090111

Authors


O'Leary, OF More by this author
Galimberti, S More by this author
Savignac, HM More by this author
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Publisher:
National Academy of Sciences
Journal:
Proceedings of the National Academy of Sciences of the United States of America
Volume:
111
Issue:
42
Pages:
15232-15237
Publication date:
2014-10-05
DOI:
EISSN:
1091-6490
ISSN:
0027-8424
URN:
uuid:83b29795-167c-48e2-84af-18747a4061e7
Source identifiers:
486921
Local pid:
pubs:486921
Language:
English
Keywords:

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