Thesis
Investigating the support mechanisms provided by macrophages in human erythropoiesis
- Abstract:
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Definitive erythropoiesis takes place within the bone marrow in erythroblastic islands, where the central macrophage plays a role in the expansion and terminal differentiation of surrounding erythroid cells. Central macrophages have been shown to promote erythropoiesis, although the precise mechanisms of how they regulate erythroblast development are still largely undefined. Furthermore, clinical and experimental studies suggest that macrophages treated with dexamethasone or IL10 may have ...
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Funding
National Health Service Blood and Transplant
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Bibliographic Details
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
Item Description
- Language:
- English
- Keywords:
- Subjects:
- UUID:
-
uuid:83a19b9d-396d-4378-8693-5c1ce01e1e65
- Deposit date:
- 2018-11-30
Terms of use
- Copyright holder:
- Diez-Sevilla, I
- Copyright date:
- 2017
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