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A7DB: A relational database for mutational, physiological and pharmacological data related to the alpha7 nicotinic acetylcholine receptor

Abstract:

Background Nicotinic acetylcholine receptors (nAChRs) are pentameric proteins that are important drug targets for a variety of diseases including Alzheimer’s, schizophrenia and various forms of epilepsy. One of the most intensively studied nAChR subunits in recent years has been a7. This subunit can form functional homomeric pentamers (a7)5, which can make interpretation of physiological and structural data much simpler. The growing amount of structural, pharmacological and physiological data...

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  • (pdf, 148.5KB)
Publication date:
2005-01-01
Local pid:
ora:767

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