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Why do euploid embryos miscarry? A case-control study comparing the rate of aneuploidy within presumed euploid embryos that resulted in miscarriage or live birth using next-generation sequencing

Abstract:

Objective

To determine whether undetected aneuploidy contributes to pregnancy loss after transfer of euploid embryos that have undergone array comparative genomic hybridization (aCGH).

Design

Case-control study.

Setting

University-based fertility center.

Patient(s)

Cases included 38 patients who underwent frozen euploid ET as determined by aCGH, resulting in miscarriage. Controls included 38 patients who underwent frozen euploid ET ...

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Publication status:
Published
Peer review status:
Peer reviewed

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Role:
Author
ORCID:
0000-0001-8766-6216
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Publisher:
Elsevier Publisher's website
Journal:
Fertility and Sterility Journal website
Volume:
106
Issue:
6
Pages:
1414-1419.e5
Publication date:
2016-09-28
Acceptance date:
2016-08-05
DOI:
ISSN:
1556-5653 and 0015-0282
Pubs id:
pubs:653601
URN:
uri:838f0109-90b0-4799-85ca-52e1e35cff01
UUID:
uuid:838f0109-90b0-4799-85ca-52e1e35cff01
Local pid:
pubs:653601

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