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Effect of oral methylprednisolone on clinical outcomes in patients with IgA nephropathy: the TESTING randomized clinical trial

Abstract:
Importance Guidelines recommend corticosteroids in patients with IgA nephropathy and persistent proteinuria, but the effects remain uncertain. Objective To evaluate the efficacy and safety of corticosteroids in patients with IgA nephropathy at risk of progression. Design, Setting, and Participants The Therapeutic Evaluation of Steroids in IgA Nephropathy Global (TESTING) study was a multicenter, double-blind, randomized clinical trial de... Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed
Version:
Accepted Manuscript

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Publisher copy:
10.1001/jama.2017.9362

Authors


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Department:
Oxford, MSD, Obstetrics & Gynaecology
More by this author
Department:
Oxford, MSD, Obstetrics & Gynaecology
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National Health and Medical Research Council of Australia More from this funder
Peking University Health Central Clinical Research Project More from this funder
Canadian Institutes of Health Research More from this funder
Publisher:
American Medical Association Publisher's website
Journal:
Journal of the American Medical Association Journal website
Volume:
318
Issue:
5
Pages:
432-442
Publication date:
2017-08-01
Acceptance date:
2017-06-29
DOI:
ISSN:
0002-9955
Pubs id:
pubs:702711
URN:
uri:8387df53-733c-4b3a-9619-9796aded6373
UUID:
uuid:8387df53-733c-4b3a-9619-9796aded6373
Local pid:
pubs:702711

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