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Tenocyte proliferation on collagen scaffolds protects against degradation and improves scaffold properties.

Abstract:

Tissue engineering scaffolds encourage cell proliferation whilst degrading to facilitate tissue regeneration. Their mechanical properties therefore change, decreasing due to scaffold degradation and increasing due to extracellular matrix deposition. This work compares the changing properties of collagen scaffolds incubated in culture medium, with and without human tenocytes, in order to investigate the relationship between degradation and tenocyte proliferation. The material properties of sca...

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Publication status:
Published

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Publisher copy:
10.1007/s10856-011-4537-7

Authors


Tilley, JM More by this author
Chaudhury, S More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, NDORMS
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, NDORMS
More by this author
Institution:
University of Oxford
Department:
Oxford, MPLS, Materials
Journal:
Journal of materials science. Materials in medicine
Volume:
23
Issue:
3
Pages:
823-833
Publication date:
2012-03-05
DOI:
EISSN:
1573-4838
ISSN:
0957-4530
URN:
uuid:8372b226-09c6-4b8f-a58c-e9c5bd9be24b
Source identifiers:
222337
Local pid:
pubs:222337

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