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Immune-based approaches to the prevention of mother-to-child transmission of HIV-1: active and passive immunization.

Abstract:

Despite more than 2 decades of research, an effective vaccine that can prevent HIV-1 infection in populations exposed to the virus remains elusive. In the pursuit of an HIV-1 vaccine, does prevention of exposure to maternal HIV-1 in utero, at birth or in early life through breast milk require special consideration? This article reviews what is known about the immune mechanisms of susceptibility and resistance to mother-to-child transmission (MTCT) of HIV-1 and summarizes studies that have use...

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Publication status:
Published

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Publisher copy:
10.1016/j.clp.2010.08.005

Authors


Lohman-Payne, B More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Experimental Medicine Division,
Journal:
Clinics in perinatology
Volume:
37
Issue:
4
Pages:
787-ix
Publication date:
2010-12-05
DOI:
EISSN:
1557-9840
ISSN:
0095-5108
URN:
uuid:835a6300-9039-414d-91f5-86ceb9557fe0
Source identifiers:
94196
Local pid:
pubs:94196

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