Journal article
Hepatitis C virus induces interferon-λ and interferon-stimulated genes in primary liver cultures.
- Abstract:
-
UNLABELLED: Hepatitis C virus (HCV) replication in primary liver cells is less robust than that in hepatoma cell lines, suggesting that innate antiviral mechanisms in primary cells may limit HCV replication or spread. Here we analyzed the expression of 47 genes associated with interferon (IFN) induction and signaling following HCV infection of primary human fetal liver cell (HFLC) cultures from 18 different donors. We report that cell culture-produced HCV (HCVcc) induced expression of Type II...
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- Publisher copy:
- 10.1002/hep.24580
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Bibliographic Details
- Journal:
- Hepatology (Baltimore, Md.)
- Volume:
- 54
- Issue:
- 6
- Pages:
- 1913-1923
- Publication date:
- 2011-12-29
- DOI:
- EISSN:
-
1527-3350
- ISSN:
-
0270-9139
- URN:
-
uuid:8354e504-15dd-4db0-8e25-2fbc77a0e302
- Source identifiers:
-
426219
- Local pid:
- pubs:426219
Item Description
Terms of use
- Copyright date:
- 2011
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