The influence of HLA-DRB1*15 on motor cortical pathology in multiple sclerosis.
AIM: Multiple Sclerosis (MS) is a common and heterogeneous CNS inflammatory demyelinating disease. The HLA-DRB1 locus may influence clinical outcome. MS cortical pathology is frequent and correlates with measures of clinical disability, including motoric dysfunction that is a predominant feature of disease progression. The influence of HLA-DRB1*15 on motor cortical pathology is unknown. METHODS: A pathologically confirmed age- and sex-matched HLA-DRB1*15+ (n=21) and HLA-DRB1*15- (n=26) MS pos...Expand abstract
- Publication status:
- Publisher copy:
- Copyright date: