Conference item icon

Conference item

miRNAs in the 14q32 cluster are involved in lapatinib resistance

Abstract:

HER2 is over-expressed in around 20-25% of breast cancers. Due to increased cell growth and differentiation signaling resulting from HER2 over-expression, this sub-type of the disease is associated with aggressive tumor progression and poor prognosis. HER2 targeted therapy has improved patient prognosis, however, only a subgroup of patients derives the optimal benefit, while other patients have refractory disease or develop resistance. miRNAs are small non coding RNAs involved in the RNAi mac...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed
Version:
Accepted manuscript

Actions


Access Document


Files:
Publisher copy:
10.1158/1538-7445.AM2017-104

Authors


Expand authors...
Publisher:
American Association for Cancer Research Publisher's website
Volume:
77
Issue:
13 Supplement
Pages:
104
Publication date:
2017-07-01
Acceptance date:
2017-01-19
DOI:
EISSN:
1538-7445
ISSN:
0008-5472
Pubs id:
pubs:918896
URN:
uri:83337bf5-1a73-4802-8471-5350811a3023
UUID:
uuid:83337bf5-1a73-4802-8471-5350811a3023
Local pid:
pubs:918896

Terms of use


Metrics


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP