Transcriptomics of cortical gray matter thickness decline during normal aging
Introduction: We performed a whole-transcriptome correlation analysis, followed by the pathway enrichment and testing of innate immune response pathway analyses to evaluate the hypothesis that transcriptional activity can predict cortical gray matter thickness (GMT) variability during normal cerebral aging.
Methods: Transcriptome and GMT data were available for 379 individuals (age range = 28–85) community-dwelling members of large extended Mexican American familie...Expand abstract
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- Peer reviewed
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- Elsevier Inc.
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- © 2013 Elsevier Inc. All rights reserved. The full text of this article is not currently available in ORA.