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Aptamers in the virologists' toolkit.

Abstract:

Aptamers are artificial nucleic acid ligands that can be generated in vitro against a wide range of molecules, including the gene products of viruses. Aptamers are isolated from complex libraries of synthetic nucleic acids by an iterative, cell-free process that involves repetitively reducing the complexity of the library by partitioning on the basis of selective binding to the target molecule, followed by reamplification. For virologists, aptamers have potential uses as tools to help to anal...

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Publication status:
Published

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Publisher copy:
10.1099/vir.0.82442-0

Authors


Journal:
The Journal of general virology
Volume:
88
Issue:
Pt 2
Pages:
351-364
Publication date:
2007-02-05
DOI:
EISSN:
1465-2099
ISSN:
0022-1317
URN:
uuid:82fe9c40-aa4d-4ac5-b6c7-ec7e7e5e8a1c
Source identifiers:
24769
Local pid:
pubs:24769

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