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Association of atrial nicotinamide adenine dinucleotide phosphate oxidase activity with the development of atrial fibrillation after cardiac surgery.

Abstract:

OBJECTIVES: Our goal was to evaluate the role of myocardial nicotinamide adenine dinucleotide phosphate (NADPH) oxidase activity and plasma markers of oxidative stress in the pathogenesis of post-operative atrial fibrillation (AF). BACKGROUND: Atrial fibrillation is a common complication of cardiac surgery, leading to increased morbidity and prolonged hospitalization. Experimental evidence suggests that oxidative stress may be involved in the pathogenesis of AF; however, the relevance of thi...

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Publication status:
Published

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Publisher copy:
10.1016/j.jacc.2007.07.085

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Institution:
University of Oxford
Department:
Oxford, MSD, RDM, Cardiovascular Medicine, BHF Centre of Research Excellence
Role:
Author
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Journal:
Journal of the American College of Cardiology
Volume:
51
Issue:
1
Pages:
68-74
Publication date:
2008-01-05
DOI:
EISSN:
1558-3597
ISSN:
0735-1097
URN:
uuid:82dd2936-f8e3-4a69-a4ee-8e696c4dc16d
Source identifiers:
104806
Local pid:
pubs:104806

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