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Journal article

High-speed biomarker identification utilizing porous silicon nanovial arrays and MALDI-TOF mass spectrometry.

Abstract:

Speed and accuracy are crucial prerequisites in the application of proteomic methods to clinical medicine. We describe a microfluidic-based nanovial array for rapid proteolytic processing linked to MALDI-TOF MS. This microscale format consumes only minute amounts of sample, and it is compatible with rapid bioanalytical protocols and high-sensitivity readouts. Arrays of vials (300 microm in diameter and 25 microm deep), isotropically etched in silicon wafers were electrochemically porosified. ...

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Publisher copy:
10.1002/elps.200500751

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Journal:
Electrophoresis
Volume:
27
Issue:
5-6
Pages:
1093-1103
Publication date:
2006-03-05
DOI:
EISSN:
1522-2683
ISSN:
0173-0835
URN:
uuid:82afb41f-062a-4e11-ae34-1f1c6a091105
Source identifiers:
365964
Local pid:
pubs:365964

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