Journal article
-308 tumor necrosis factor (TNF) polymorphism is not associated with survival in severe sepsis and is unrelated to lipopolysaccharide inducibility of the human TNF promoter.
- Abstract:
-
Tumor necrosis factor (TNF) is recognized as a central mediator of sepsis, septic shock, and multiple organ failure. These host reactions are associated with increased TNF levels in circulation, presumably due to increased TNF production. A previously described nucleotide variation at position -308 in the promoter region of the human TNF gene was shown to be associated with the clinical outcome of malaria. In this study we addressed the relevance of the -308 polymorphism for expression of the...
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Bibliographic Details
- Journal:
- Journal of inflammation
- Volume:
- 46
- Issue:
- 1
- Pages:
- 42-50
- Publication date:
- 1995-01-01
- ISSN:
-
1078-7852
- Source identifiers:
-
374945
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:374945
- UUID:
-
uuid:82a941ef-c1ec-42e4-8c18-9c23613e670a
- Local pid:
- pubs:374945
- Deposit date:
- 2013-11-16
Terms of use
- Copyright date:
- 1995
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