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Rosette formation of Plasmodium falciparum-infected erythrocytes from patients with acute malaria.

Abstract:

Noninfected erythrocytes form rosettes around those infected with trophozoites and schizonts of Plasmodium falciparum in vitro. These rosettes are thought to contribute to the microvascular obstruction which underlies the pathophysiology of severe falciparum malaria. To determine whether the percentage of infected erythrocytes forming rosettes for a parasite isolates in vitro correlates with the in vivo severity of disease, we studied the rosette formation behavior of 35 isolates of P. falcip...

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Publication status:
Published

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Authors


Silamut, K More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Thailand/Laos MOP
Journal:
Infection and immunity
Volume:
59
Issue:
6
Pages:
2135-2139
Publication date:
1991-06-05
EISSN:
1098-5522
ISSN:
0019-9567
URN:
uuid:82a45e0e-ad68-478a-8d6d-35e0044a20f6
Source identifiers:
43602
Local pid:
pubs:43602

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