Journal article
Genetic evaluation of the performance of malaria parasite clearance rate metrics
- Abstract:
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Accurate measurement of malaria parasite clearance rates (CRs) following artemisinin (ART) treatment is critical for resistance surveillance and research, and various CR metrics are currently used. We measured 13 CR metrics in 1472 ART-treated hyperparasitemia infections for which 6-hour parasite counts and parasite genotypes (93 single nucleotide polymorphisms [SNPs]) were available. We used heritability to evaluate the performance of each metric. Heritability ranged from 0.06 ± 0.06 (SD) fo...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Version of record, pdf, 188.8KB)
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- Publisher copy:
- 10.1093/infdis/jit165
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Authors
Funding
Wellcome Trust
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NIAID NIH HHS
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NCRR NIH HHS
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Bibliographic Details
- Publisher:
- Oxford University Press Publisher's website
- Journal:
- Journal of Infectious Diseases Journal website
- Volume:
- 208
- Issue:
- 2
- Pages:
- 346–350
- Publication date:
- 2013-04-16
- DOI:
- ISSN:
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1537-6613 and 0022-1899
- Pmid:
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23592863
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:395915
- UUID:
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uuid:82a29bfc-9bf6-4c34-8197-1cdd551cb09c
- Local pid:
- pubs:395915
- Deposit date:
- 2016-09-24
Terms of use
- Copyright holder:
- Standwell Nkhoma et al
- Copyright date:
- 2013
- Notes:
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This is an Open Access article distributed under the terms of the Creative
Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/3.0/), which permits non-commercial reproduction and distribution of the work, in any
medium, provided the original work is not altered or transformed in any way, and that the work
properly cited.
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