- Abstract:
-
Accurate measurement of malaria parasite clearance rates (CRs) following artemisinin (ART) treatment is critical for resistance surveillance and research, and various CR metrics are currently used. We measured 13 CR metrics in 1472 ART-treated hyperparasitemia infections for which 6-hour parasite counts and parasite genotypes (93 single nucleotide polymorphisms [SNPs]) were available. We used heritability to evaluate the performance of each metric. Heritability ranged from 0.06 ± 0.06 (SD) fo...
Expand abstract - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Publisher's version
- Files:
-
-
(pdf, 188.8KB)
-
- Publisher copy:
- 10.1093/infdis/jit165
-
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- Publisher:
- Oxford University Press Publisher's website
- Journal:
- The Journal of Infectious Diseases Journal website
- Volume:
- 208
- Issue:
- 2
- Pages:
- 346–350
- Publication date:
- 2013-04-16
- DOI:
- ISSN:
-
0022-1899 and 1537-6613
- Pubs id:
-
pubs:395915
- URN:
-
uri:82a29bfc-9bf6-4c34-8197-1cdd551cb09c
- UUID:
-
uuid:82a29bfc-9bf6-4c34-8197-1cdd551cb09c
- Local pid:
- pubs:395915
- Paper number:
- 2
- Language:
- English
- Keywords:
- Copyright holder:
- Standwell Nkhoma et al.
- Copyright date:
- 2013
- Notes:
-
This is an Open Access article distributed under the terms of the Creative
Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/3.0/), which permits non-commercial reproduction and distribution of the work, in any
medium, provided the original work is not altered or transformed in any way, and that the work
properly cited.
Journal article
Genetic evaluation of the performance of malaria parasite clearance rate metrics
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