Journal article icon

Journal article

MicroRNA-21 limits uptake of Listeria monocytogenes by macrophages to reduce the intracellular niche and control infection

Abstract:

MiRNAs are important post-transcriptional regulators of gene expression. MiRNA expression is a crucial part of host responses to bacterial infection, however there is limited knowledge of their impact on the outcome of infections. We investigated the influence of miR-21 on macrophage responses during infection with Listeria monocytogenes, which establishes an intracellular niche within macrophages. MiR-21 is induced following infection of bone marrow-derived macrophages (BMDMs) with Listeria....

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

Actions


Access Document


Files:
Publisher copy:
10.3389/fcimb.2017.00201

Authors


More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDORMS; KIR
Role:
Author
ORCID:
0000-0002-1737-0046
More by this author
Role:
Author
ORCID:
0000-0003-3361-4140
Expand authors...
Publisher:
Frontiers Media Publisher's website
Journal:
Frontiers in Cellular and Infection Microbiology Journal website
Volume:
7
Pages:
Article: 201
Publication date:
2017-05-23
Acceptance date:
2017-05-05
DOI:
ISSN:
2235-2988
Pubs id:
pubs:746817
URN:
uri:828996a9-a88b-4b39-8a9b-695b3e64c728
UUID:
uuid:828996a9-a88b-4b39-8a9b-695b3e64c728
Local pid:
pubs:746817

Terms of use


Metrics


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP