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PET evidence for a role of the basal ganglia in patients with ring chromosome 20 epilepsy.

Abstract:

BACKGROUND: Studies in animal models and epileptic patients have suggested that circuits of the basal ganglia may control epileptic seizures and that striatal dopaminergic transmission plays a key role in seizure interruption. Ring chromosome 20 (r[20]) epilepsy is a very homogenous type of epilepsy and is clinically characterized by long-lasting seizures suggesting a dysfunction in the seizure control system. The hypothesis that these long-lasting seizures are associated with a reduction of ...

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Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Role:
Author
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Journal:
Neurology
Volume:
63
Issue:
1
Pages:
73-77
Publication date:
2004-07-01
DOI:
EISSN:
1526-632X
ISSN:
0028-3878
Source identifiers:
241464

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