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Higher parental occupational social contact is associated with a reduced risk of incident pediatric type 1 diabetes: Mediation through molecular enteroviral indices

Abstract:

We aimed to examine the association between parental occupational social contact and hygiene factors on type 1 diabetes (T1D) risk and possible mediation of these effects through child enteroviral infection. We interviewed 333 incident T1D cases and 660 controls from 2008–2011 in Melbourne, Australia. Enteroviral indices (ribonucleic acid by reverse transcription polymerase chain reaction and Coxsackie B virus antibody levels) in peripheral blood were measured in nested case control samples. ...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1371/journal.pone.0193992

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ORCID:
0000-0002-6581-3657
Cameron, FJ More by this author
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Australian Research Council More from this funder
Arthritis Australia More from this funder
Diabetes Australia More from this funder
Rebecca L. Cooper Medical Research Foundation More from this funder
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Publisher:
Public Library of Science Publisher's website
Journal:
PLoS ONE Journal website
Volume:
13
Issue:
4
Pages:
Article: e0193992
Publication date:
2018-04-17
Acceptance date:
2018-02-22
DOI:
EISSN:
1932-6203
Pubs id:
pubs:844155
URN:
uri:826a0732-630d-42de-94d7-b1b6b87f4b35
UUID:
uuid:826a0732-630d-42de-94d7-b1b6b87f4b35
Local pid:
pubs:844155
Language:
English

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