- Abstract:
-
The course of immune maturation has evolved to favour survival at each stage of development in early life. Fetal and neonatal immune adaptations facilitate intrauterine survival and provide early postnatal protection against extracellular pathogens, but they leave infants susceptible to intracellular pathogens such as viruses that are acquired perinatally. This Review focuses on three such pathogens--HIV, hepatitis B virus and cytomegalovirus--and relates the differential impact of these infe...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1038/nri3277
-
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- Journal:
- Nature reviews. Immunology
- Volume:
- 12
- Issue:
- 9
- Pages:
- 636-648
- Publication date:
- 2012-09-05
- DOI:
- EISSN:
-
1474-1741
- ISSN:
-
1474-1733
- URN:
-
uuid:825b21d4-59f3-437c-b379-09ed368712a0
- Source identifiers:
-
349777
- Local pid:
- pubs:349777
- Copyright date:
- 2012
Journal article
The impact of differential antiviral immunity in children and adults.
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